Senior Bioinformatician

Were seeking a Senior Bioinformatician to lead bioinformatics strategy and decision-making across the entire assay lifecycle from in-silico design and design verification to validation and post-market genomic surveillance.

In this role, youll ensure assay targets, primers, probes, and controls are scientifically robust, regulatory-compliant, and future-proof across qRT-PCR, multiplex, isothermal, immuno-based, and Point-of-Care diagnostic platforms.

Key Responsibilities

• Lead in-silico design and verification of molecular and PoC assays
• Design and evaluate targets, primers, probes, internal/process controls, and reference sequences
• Perform inclusivity/exclusivity, variant, mutation, and cross-reactivity analyses
• Assess target conservation, multiplex compatibility, mismatch tolerance, and secondary structure risks
• Define bioinformatics acceptance criteria aligned with MIQE 2.0, CLSI, ISO 13485 & ISO 14971
• Support DOE-based optimization, risk management, and design change impact assessments
• Contribute to validation readiness (LoD, robustness, interference studies)
• Monitor global genomic datasets to support post-market surveillance and ongoing assay performance

Qualifications

• M.Sc./M.Tech/Ph.D. in Bioinformatics, Genomics, Computational Biology, Biotechnology, or related field
• 37 years of industry experience in bioinformatics-driven assay design, validation, or genomic surveillance
• Experience working in regulated IVD environments
• Strong cross-functional communication skills and regulatory mindset