LCMS/HRMS Scientist

Job Title: LCMS Scientist for Peptide & Technology-Based Product Characterization

Job Description:

We are seeking a skilled and detail-oriented LCMS Scientist to join our Analytical Characterization Team, focusing on peptide-based products as well as other technology-driven formulations.

Company Overview

Orbicular Pharmaceutical Technologies Pvt. Ltd. is a research-driven organization specializing in the development of niche generics and specialty pharmaceutical products. Our CI-TOP SPIN strategy focuses on Complex Injectables, Topicals, Ophthalmic, Parenteral, Nasal Sprays, and Inhalation products, targeting complex and high-value segments.

With a core focus on formulation and drug delivery technologies, Orbicular offers diverse solutions across therapeutic areas and dosage forms. We collaborate with both national and international pharmaceutical companies and are backed by seasoned techno-entrepreneurs and leading scientists. Our proven track record spans the full lifecycle from concept to commercialization of innovative pharmaceutical products.

Website : www.orbicular.co.in

Qualifications : M.Sc/B.Pharm/M.Pharma/Ph.D

Experience : 512 years of experience

Dept : Analytical Research

Key Responsibilities:

• Perform intact mass analysis and primary structure characterization of peptides.
• Conduct advanced studies including:

- Disulfide bond mapping

- Sequence confirmation

- D/L isomer differentiation

• Develop and validate LCMS/MS methods for peptide analysis.
• Conduct impurity profiling for peptide-related impurities using LC-HRMS.
• Identify unknown impurities by determining mass and amino acid sequence.
• Support extractables and leachables studies using mass spectrometry.
• Operate and interpret data from SEC-HPLC and SEC-MALS (if applicable).
• Collaborate closely with CROs and regulatory teams.
• Contribute to regulatory submissions (e.g., ANDA, IND, BLA) with high-quality analytical data.
• Prepare and review analytical reports, ensuring data integrity and compliance with GLP/GMP standards.

The above-mentioned JD and responsibilities include, but are not limited to, the job.