Bioprocess Engineer

Job Title: Chemical Engineer Bioprocess & Process Development

Location: Bengaluru, India

Employment Type: Full-time

Role Overview

We are establishing a dedicated Process Development capability within our biotechnology

R&D facility to support the development and industrialisation of renewable and sustainable

natural aroma ingredients for the flavour and fragrance industry.

We seek a Chemical Engineer with strong hands-on experience in bioprocess design,

fermentation, biocatalysis, and downstream processing, capable of bridging experimental

R&D with industrial process, equipment, and utility design at pilot and production scale.

This position operates at the interface between R&D and Manufacturing and will play a key

role in:

Translating laboratory processes into scalable, robust, and economically viable

manufacturing processes

Leading scale-up, technology transfer, and process optimisation activities

Contributing to the establishment of a Process Development group responsible for

scale-up strategy, process design, and plant interface

Key Responsibilities

Bioprocess & Fermentation Development

Design, execute, and optimise fermentation and biocatalytic processes for aroma

ingredient production

Develop scalable bioprocess flowsheets from laboratory to pilot and manufacturing

scale

Define and optimise media composition, feeding strategies, pH, temperature,

aeration, agitation, and operating modes (batch, fed-batch, continuous where

appropriate)

Perform mass and energy balances for upstream and downstream operations

Define scale-up criteria related to mixing, oxygen transfer, heat removal, shear, and

residence time

Downstream Processing &; Product Recovery

Develop and optimise recovery and purification strategies including liquidliquid

extraction, phase separation, distillation, adsorption, and chromatography

Translate laboratory purification schemes into industrially viable operations

Evaluate solvent selection, solvent recovery, waste streams, and environmental

impact

Process Design & Equipment Interface

Define preliminary equipment sizing and utility requirements for pilot and production

scale

Translate experimental data into process design inputs for internal and external

engineering teams

Support selection of reactors, fermenters, separators, heat exchangers, and auxiliary

equipment

Contribute to layout concepts and plant integration discussions

Scale-Up, Technology Transfer & Plant Support

Plan and execute scale-up and pilot trials in collaboration with R&D and

manufacturing

Prepare and implement technology transfer packages from R&D to production

Develop SOPs, batch records, process descriptions, and scale-up reports

Support troubleshooting of process deviations at pilot and plant scale

Drive continuous improvement, debottlenecking, and yield optimisation initiatives

Process Economics & Feasibility

Provide technical inputs for costing, feasibility studies, and business cases

Build and maintain CAPEX and OPEX models for new product processes

Identify opportunities for cost reduction, yield improvement, and energy optimisation

Cross-Functional Collaboration

Work closely with microbiologists, chemists, analytical teams, and manufacturing

Interface with external engineering and equipment suppliers as required

Contribute to internal best practices for process development and scale-up

Required Qualifications

M.Tech or PhD in Chemical Engineering

38 years of relevant experience in bioprocessing, fermentation, biocatalysis, or

process development

Hands-on experience with bioreactors/fermenters at laboratory, pilot, and preferably

industrial scale

Strong understanding of reaction engineering, transport phenomena,

thermodynamics, and separation processes

Demonstrated experience translating laboratory processes to pilot or plant scale

Experience developing CAPEX/OPEX models and techno-economic assessments

Experience Required

Exposure to aroma, flavour, fragrance, fine chemicals, or specialty chemicals

Experience with process simulation and modelling tools (Aspen Plus, Matlab or

equivalent)

Familiarity with Design of Experiments (DoE) and data-driven optimisation

Experience operating in cross-functional R&DManufacturing environments

Send in your CV at Dimpy@tojovikas.com